Scab on sole of foot in a 30-year-old cisgender man with HMPX, imaged at lesion day 9.
Located on the sole of the foot is a 3-mm nonerythematous scab that is nontender and nonpruritic. This lesion, part of a secondary crop of lesions, developed on illness day 10.
There was no history of immunocompromising conditions or medications. This man was on Truvada for HIV pre-exposure prophylaxis. He also received Imvamune for HMPX pre-exposure prophylaxis 3 days before illness onset.